Doctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
AST (Aspartate Aminotransferase)
AST monitoring is particularly important with age, as the liver and heart become more susceptible to conditions that elevate this enzyme. Medication interactions and age-related changes can influence AST levels, making regular testing a valuable part of health management for seniors.
What It Measures
AST is an enzyme involved in amino acid metabolism, found in the liver, heart, skeletal muscles, kidneys, and brain. When cells in these organs are damaged, AST is released into the bloodstream.
This test measures the concentration of AST in your blood. Unlike ALT, which is more liver-specific, elevated AST can originate from multiple tissues. The AST:ALT ratio is often used to help differentiate between causes of liver enzyme elevation.
Why It Matters
AST levels provide important information about the health of your liver, heart, and muscles. Elevated levels may be associated with conditions such as hepatitis, cirrhosis, heart attack, or muscle injury.
When evaluated alongside ALT, the AST:ALT ratio can help your healthcare provider identify the underlying cause of liver enzyme elevation. An AST:ALT ratio greater than 2:1, for instance, may suggest alcohol-related liver damage.
When to Test
Testing may be recommended as part of a liver function panel, when liver disease is suspected, or when monitoring the effects of medications that may affect the liver.
AST testing may also be indicated after a suspected heart attack, in cases of unexplained muscle pain, or when evaluating symptoms such as fatigue, jaundice, or abdominal discomfort.
Symptoms
Low Levels
High Levels
Jaundice (yellowing of skin or eyes)
Abdominal pain, particularly in the upper right area
Dark urine
Nausea or loss of appetite
Recommendations
Male
Normal AST indicates healthy liver and heart function. Maintain healthy lifestyle habits.
Elevated AST may indicate liver or heart muscle damage. Consider further evaluation including imaging and additional liver tests.
Female
Normal AST indicates healthy liver and heart function. Maintain healthy lifestyle habits.
Elevated AST may indicate liver or heart muscle damage. Consider further evaluation including imaging and additional liver tests.
Lifestyle Tips
Limit alcohol consumption, as chronic excessive drinking is a well-established cause of elevated AST levels. Maintain a healthy body weight through balanced nutrition and regular physical activity to support liver health.
Discuss all medications and supplements with your healthcare provider, as some may contribute to elevated liver enzymes. Allow adequate recovery time between intense exercise sessions, as vigorous physical activity can temporarily raise AST levels.